Polineuropatia associada a hipotireoidismo em cães: Relato de seis casos

13 de agosto de 2020

Hypothyroid associated polyneuropathy in dogs:Report of six cases

Autores

Adriana Patricia Suraniti, Liliana Rosa Gilardoni, Mabel Graciela Ramallal, Marcelo Echevarría, Mary Marcondes

Resumo

Seis Dobermans Pinscher, entre seis e oito anos de idade, foram encaminhados ao Hospital Veterinário da Faculdade de Ciências Veterinárias da Universidade de Buenos Aires. O exame neurológico revelou tetraparesia com incapacidade para andar, diminuição do tono muscular e de reflexos miotáticos em todos os cães. Os níveis de colesterol, creatina quinase e fosfatase alcalina encontravam-se de moderada a acentuadamente elevados. As velocidades de condução nervosa do nervo tibial estavam diminuídas em todos os cães. Os níveis séricos basais de T4 livre e TSH foram determinados por radioimunoensaio e, embora os valores de T4 livre estivessem dentro dos limites de normalidade, em todos os cães o TSH estava elevado.

Palavras-chave

Hormônios tireoidianos.Velocidade de condução nervosa motora.Neuropatia.

Abstract

Six Doberman Pinscher, between six and eight years of age, were presented to the Veterinary Hospital from Faculty of Veterinary Science of The University of Buenos Aires. Neurological examination revealed tetraparesis with inability to walk, decreased muscle tonus and myotatic reflexes in all dogs. Serum cholesterol levels, creatine kinase and alkaline phosphatase activities were mildly to markedly elevated, and tibial motor nerve conduction velocities were slow in all dogs. Basal measurements of free T4 and TSH were determined by radioimmunoassay. Although fT4 values were within normal range,in all dogs TSH values were elevated. Based on this results, hypothyroidism was diagnosed and a supplementation therapy was established with oral levothyroxine (T4). Two weeks after treatment has been started, all patients had an improvement in clinical signs,and within a month gait became normal, as well as muscular tonus and spinal reflexes.

Keywords

Thyroid hormones. Motor nerve conduction velocity.Neuropath

 

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