Ionized Hypocalcemia in Critically Ill Dogs
Hipocalcemia ionizada em cães criticamente enfermos
M.K. Holowaychuk, B.D. Hansen, T.C. DeFrancesco, and S.L. Marks
Hypothesis: iHCa occurs in critically ill dogs, is more prevalent in dogs with systemic inflammatory response syndrome (SIRS) or sepsis, and is associated with longer hospital stays and higher mortality.
Animals: One hundred and forty-one client-owned dogs admitted to a companion animal intensive care unit (ICU) in a veterinary teaching hospital.
Methods: Prospective observational study of sequentially enrolled dogs. Blood was collected and analyzed within an hour of admission from all dogs presented to the ICU that met study inclusion criteria.
Results: The incidence of iHCa (iCa < 1.11 mmol/L) was 16%. The presence of iHCa was associated with longer ICU (P = .038) and hospital (P =.012) stays but not with decreased survival (P = .60). Dogs with sepsis as defined by >=3 SIRS criteria and a positive culture were more likely to have iHCa (P = .050).
Conclusions and Clinical Relevance: In dogs not previously treated with fluids or blood products intravenously, the finding of iHCa upon admission to the ICU predicted a longer duration of ICU and hospital stay. Septic dogs with positive cultures were more likely to have iHCa.
Canine; Critical care; Intensive care medicine; Sepsis; Systemic inflammatory response syndrome; Trauma.
Canino, cão, intensivísimo, emergência, septicemia síndrome da resposta inflamatória sistêmica