Philip Krawec and Adesola Odunayo
Cystocentesis (ie, obtaining urine directly from the urinary bladder by inserting a needle through the body
wall) is common and considered the ideal method for obtaining urine for urinalysis and culture and susceptibility testing. Cystocentesis typically helps prevent contamination (eg, from bacteria, RBCs, WBCs, or debris from the lower urinary tract and perineum) that can occur with voided or catheterized urine samples.
Diagnosis of bacterial cystitis is somewhat simplified through cystocentesis, as samples through this method should be sterile3; quantitative bacterial counts should be analyzed when evaluating voided samples. Although frequently iatrogenic and self-limiting, hematuria may be noted in cystocentesis samples