Correlation between renal histopathology and renal ultrasound in dogs

30 de abril de 2020

Silvia Burtia
, Alessandro Zottia
, Federico Bonsembiantea,b
, Giorgia Mastellaroa
,
Tommaso Banzatoa,⁎

Keywords:
Kidney, Ultrasound, Pathology, Rins, ultrasson, patologia, renal

Fifty-three privately owned dogs were included in the study. Ultrasonography of the kidneys was performed ante
mortem. All the dogs died or were euthanized for reasons unrelated to this study. Histopathology of both kidneys
was performed, and a degeneration and an inflammation score ranging from zero to two was assigned by
consensus between two pathologists. A numerical score based on a three level semi-quantitative scale (0, 0.5, 1)
was assigned by consensus between two of the authors to the following ultrasonographic abnormalities: corticomedullary definition, echogenicity of the renal cortex, echogenicity of the medulla, renal shape, cysts, scars,
mineralizations, subcapsular perirenal fluid accumulation, pyelectasia. The scores deriving from the consensus
were summed to create a summary index called renal ultrasound score (RUS). Statistically significant differences
in cortico-medullary definition, echogenicity of the renal cortex, echogenicity of the medulla, renal shape, scars
and pyelectasia were evident between the degeneration score groups. There were significantly different distributions of cortico-medullary definition, renal shape and scars between the inflammatory score groups. There
were statistically significant differences in the RUS between the degenerative score groups (F = 24.154, pvalue < .001). Post-hoc tests revealed significant differences between all groups. There were no significant
differences in the RUS between the inflammatory score groups (F = 1.312, p-value = .264). Post-hoc tests
revealed no significant differences between groups. The results of the present study suggest that the number and
severity of the ultrasonographic abnormalities are correlated with the severity of the kidney degeneration. On
the other hand, inflammation showed poor influence on the ultrasonographic appearance of the kidneys.

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