Clinical Application of Serum Eye Drops for Herpetic Keratitis in Cats: A Pilot Study.

23 de abril de 2021

Aplicação clinica de soro autólogo como colírio em gatos com ceratite herpética: estudo piloto

Abstract

This study was performed to identify the clinical effect of using serum eye drops as an adjuvant treatment for herpetic keratitis in cats. We reviewed the medical records of seven cats (9 eyes) that were diagnosed with herpetic keratitis based on the clinical features and history. All cases showed recurrent or unresponsive corneal ulcers that had not healed after 3 weeks with conventional treatment. Thus they received supplementary treatment with serum eye drops. We also assessed the correlations between the defect duration prior to serum administration and the duration to healing after the serum treatment. The mean age of the cats was 1.43 ± 2.26 years. The cats received various treatments including topical antibiotics (n = 9), antivirals (n = 8), non-steroidal anti-inflammatory eye drops (n = 2), and artificial tears (n = 2). The mean duration from ulcerative keratitis onset to serum administration was 24.78 ± 7.16 days. All cases were completely healed without ulcer relapse for 3 months. The mean duration to healing was 19.33 ± 2.26 days, and the duration from ulcerative keratitis onset to serum administration was significantly correlated with the duration to healing after the treatment (r2 = 0.895, P<0.01). Our results showed that the serum eye drops were effective as an adjuvant treatment for herpetic keratitis in cats that were unresponsive to conventional treatments, particularly in cats with recent ulcers.

Keywords

Feline, herpetic keratitis, serum, allogeneic, autologous, cornea, cat.

Palavras chave:

Felino, ceratite herpética, soro, halogênico, autólogo, cornea, gato

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