Cardiac Lesions in 30 Dogs Naturally Infected With Leishmania infantum chagasi

8 de agosto de 2020

Lesões cardíacas em 30 cães naturalmente Infectado com Leishmania infantum chagasi

Autores

F. A. Rosa, J. H. A. C. Leite, E. T. Braga, P. R. R. Moreira, F. H. Baltazar, A. W. Biondo4,5, P. P. M. Padua, R. O. Vasconcelos, A. A. Camacho, W. L. Ferreira, G. F. Machado, M. Marcondes

Abstract

The hearts of 30 dogs naturally infected with Leishmania infantum chagasi were evaluated histologically and immunohistochemically. Myocardial lesions were detected in all dogs, including lymphoplasmacytic myocarditis (27/30), myonecrosis (24/30), increased interstitial collagen (22/30), lepromatous-type granulomatous myocarditis (7/30), fibrinoid vascular change (3/30), and vasculitis (1/30). The parasite was detected in the hearts of 20 of 30 dogs. The number of parasitized cells correlated with the intensity of the inflammation and with the number of granulomas. The results indicate that cardiac lesions are prevalent in dogs with naturally occurring leishmaniasis even in the absence of clinical signs of cardiac disease.

Keywords

dog, myocarditis, immunohistochemistry, leishmaniasis

Palavras-chave

cão, miocardite, imunohistoquímica, leishmaniose

 

 

 

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