Autologous serum for ocular surface diseases

23 de abril de 2021

Soro autólogo para doenças da superfície ocular


Guilherme Goulart Quinto, Mauro Campos, Ashley Behrens

Autologous serum has been used to treat dry eye syndrome for many years. It contains several growth factors, vitamins, fibronectin and other components that have been considered important for corneal and conjunctival integrity. Serum eye drops are usually prepared as an unpreserved blood solution. The serum is by nature well tolerated and its biochemical properties are somewhat similar to natural tears. Autologous serum eye drops have been reported to be effective for the treatment of severe dry eye-related ocular surface disorders (Sjögren’s syndrome), and also other entities such as superior limbic keratoconjunctivitis, graft-versus-host disease, Stevens-Johnson syndrome, ocular cicatricial pemphigoid, recurrent or persistent corneal erosions, neurotrophic keratopathy, Mooren’s ulcer, aniridic keratopathy, filtering blebs after trabeculectomy, and postkeratorefractive surgery. The purpose of this study is to review the recently published literature on ocular surface diseases treated with human
autologous serum eye drops


Corneal diseases/therapy; Conjunctival diseases/therapy; Lacrimal apparatus/ abnormalities; Serum; Ophthalmic solutions/therapeutic use

Palavras chave

Doença corneal, tratamento, doenças conjuntivais, aparato lacrimal, anormalidades, soro, solução oftalmológica, uso terapêutico

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