2010 ACVIM Small Animal Consensus Statement on Leptospirosis: Diagnosis, Epidemiology, Treatment, and Prevention

Consenso sobre Leptospirose para Pequenos Animais da ACVIM 2010: Diagnóstico, Epidemiologia, Tratamento e Prevenção

Autores:

J.E. Sykes, K. Hartmann, K.F. Lunn, G.E. Moore, R.A. Stoddard, R.E. Goldstein

Abstract:

This report offers a consensus opinion on the diagnosis, epidemiology, treatment, and prevention of leptospirosis in dogs, animportant zoonosis. Clinical signs of leptospirosis in dogs relate to development of renal disease, hepatic disease, uveitis, andpulmonary hemorrhage. Disease may follow periods of high rainfall, and can occur in dogs roaming in proximity to watersources, farm animals, or wildlife, or dogs residing in suburban environments. Diagnosis is based on acute and convalescentphase antibody titers by the microscopic agglutination test (MAT), with or without use of polymerase chain reaction assays.There is considerable interlaboratory variation in MAT results, and the MAT does not accurately predict the infectingserogroup. The recommended treatment for optimal clearance of the organism from renal tubules is doxycycline, 5 mg/kg POq12h, for 14 days. Annual vaccination can prevent leptospirosis caused by serovars included in the vaccine and is recommendedfor dogs at risk of infection.

Keywords:

Hepatitis;Leptospira interrogans;Nephritis; Zoonosis;leptosirose

Palavras-chave:

diagnóstico, nefrite, doença renal aguda, injúria, hepatite